Research findings of - G - 7 CAPSULES

Studies and evaluation done on G - 7 Capsule presented here are proprietary formulation of Dr. JRK's Siddha Research and Pharmaceuticals Pvt Ltd

Anti allergenic study of G - 7 Capsule

G-7 capsule, the proprietary formulation of Dr.JRK's Siddha Research and Pharmaceuticals Pvt.Ltd., Kuntrathur, Chennai was studied. Both In vitro and In vivo study was carried out for confirmation. The peritoneal mast cells were used for the in vitro study. The isolated mast cells were maintained in RPMI 1640 tissue culture medium in a flat bottom multi welled micro titre plate. The cells were treated with different concentrations of G-7 extract prepared in Hans buffer with the aid of Myosol as solvent. The concentrations of the G-7 tested were 2,10,20,40 and 50 µg / ml of medium. The treatment time was kept constant for 20 minutes. Later, the cells were challenged with sensitized IgE and the opsonized allergen. The amount of histamines and neutral proteases released by the G-7 treated and untreated mast cells were quantified. Histamine quantification was done by radio immune assay using radio tagged antihistamines using Scintillation counter. Similarly, attempts were made to check the histamine release by using specific immune staining.

Treatment Quantity of Histamine released Protease activity Treated Group 40µg / ml 60 IU / 100 cells 18.3 mg / ml / minute Untreated Group 123 IU / 100 cells 28 mg / ml / minute

Proteolytic activity was determined by substrate-enzyme reaction assay. The end product the tyrosine released as a result of proteolyses of collagen is determined. Determination of mechanism of action The IgE – FC receptor site in the mast cells were blocked with a dummy protein prior to G-7 treatment. The dummy protein is later removed and was challenged with sensitized IgE. The findings revealed that the degranulation inhibition is mediated through IgE receptor binding by the G-7 moiety. In vivo study Dust inhalation study For in vivo confirmation of the effect of G-7 in mast cell degranulation inhibition, dust inhalation study was conducted using Rabbit model. Rabbits were pre-treated with G-7 for 15 days. Later the treated and untreated animals were challenged with house dust through a nebulizer in a dust inhalation chamber. The histamine released in the system is assayed as mentioned above. The findings of the study reveal that G-7 offers greater protective effect to the mast cells from degranulation during the allergen exposure Inhibition of broncho spasm during allergen exposure and anaphylactic shock in the case of - G -7 treated animals also observed in a separate study. Mechanism of action of G - 7 on mast cells

Hepatoprotector

Hepatoprotection or antihepatotoxicity is the ability to prevent damage to the liver.

Liver damage causes serious metabolic disorders, immune response, detoxification functions and antimicrobial protection. Therefore, the problem of finding new high effective drugs for the restoration and normalization of liver function is extremely urgent.

BEKAY for Hepato (Liver) Protection:

Problem Solution Usage instruction Liver protection Bekay capsules Adult: one capsule in morning and two capsules at night after food Children: above 10 years: one capsule a day after food.

Bekay - Proven hepato protective effect

The hepato protective effector Bekay was studied after inducing the hepatic damage with CCl4. The findings clearly established the therapeutic effect of Bekay in liver protection. For more details, please visit us, http://www.jrksiddha.com

Psorolin - Ointment

Proved ‘Topical Psorolin Ointment’ is very effective for FungalInfections (Tinea versicoraris).

Psorolin Ointment is adjuvant to 777 Oil. Psorolin Ointment is very effective during the scaling stage of psoriasis. It controls hyperkeratosis. Clinical trials at the Department of Dermatology, Madras Medical College, Chennai. Proved ‘Topical Psorolin Ointment’ is very effective for Psoriasis & Fungal Infections (Tinea versicoraris). It has a dark magenta colour with natural odour, presented in petroleum jelly base.

Composition

Oil extracts of
Wrightia tinctoria ( Swetha kutaja)	:	33 %
Cynadon dactylan ( Dhoorva)	:	33 %
Petroleum jelly base	:	33 %

Direction for use(for surface application only)
Apply on lesions at bedtime during the scaling stage all types of Psoriasis.

For more details, please visit us,

http://www.jrksiddha.com

Dolowhite pain balm

Dolowhite pain relief pain balm dolowhite for acutemuscular skeletal pain, relieves stiffness and pain in the joints, restores normal mobility, amongst the most common problems of middle-aged men and women is low back pain and osteo arthritis. Dolobalm is uniquely formulated in an emulsion bays where the outer face water cools the skin and enhances the absorption of actives. These bees wax form as an occlusive layer prevent their evaporation.

Dolowhite contains

1. Extract of Aloe Vera
2. Extract of Clerodendron phlomoides
3. Camphor
4. Oil of Sesamum indicum
5. Gugglu

Use Dolowhite for a period of 12 to 16 weeks in the prescribed manner provides a lasting solution to the problem of Rheumatoid Arthritis.

For more details, please visit us,

http://www.jrksiddha.com

  

EVE FRESH

 Eve fresh contains extracts of Curcuma zedoaria and Aloe vera a combination found to be effective in decreasing melanin synthesis through tyrosinase inhibition.

Evefresh is a specially formulated cream to give the twin advantage of fairness and freshness. Eve fresh uses time tested herbs like Curcuma zedoaria turmeric and Aloe vera to gift you a fair, healthy, and glowing skin that you would always be proud of. Aloe vera is a natural moisturizer and acts like a sunscreen. Aloe vera also keeps you fresh all day. The goodness of Curcuma zedoaria is known to enhance the complexion in a natural way. The antimicrobial property of Curcuma zedoaria also helps to keep the skin free from infections and blemishes.

For more details, please visit us,

http://www.jrksiddha.com

 

 

Vitiligo treatment India

Vitiligo is a continual and long term skin problem that produces white depigmentation patches that develop and enlarge only in certain sections of the skin. 

These white patches appear because the patient has very little or no skin cells - called melanocytes - which are the cells in charge of producing the skin pigmentation, called melanin, which gives the color of the skin and protects it from the sun´s UV rays.

What are the causes of vitiligo?

•        An autoimmune disorder - the patient's immune system becomes overactive, and destroys the melanocytes
•          Genetic oxidative stress imbalance
•          A stressful event
•          Harm to the skin due to a critical sunburn or cut
•          Exposure to certain chemicals
•          A neural cause
•          A viral cause

Vitiligo treatment India:

Apply Tolenorm oil/ointment on the depigmented region of the skin once a day and expose to sunlight after half an hour of application for about 3-5 minutes. Continue application until complete repigmentation.\

For more details, please visit us,

http://www.jrksiddha.com/vitiligo.aspx