S.I.V.A Herbal Drops

Solution for Immune Related Problems

Problem Solution Usage instruction Immune Boosting S.I.V.A Herbal Drops Adult: 10 drops preferably honey in empty stomach twice a day. S.I.V.A Herbal Tonic for Pediatric use 1 to 3 years- 10ml once daily before food.4 years and above: 10ml twice daily before food.

In today's jet-set life style, due to change of food habits from natural to junk , shift of work hour drastically and hence change of biological clock of our body , home and work related stress etc coupled with continuous exposure to different types of pollution, there is obvious onslaught of whole host of germs and microbes round the clock on our body . Hence you will agree that developing a strong, robust body- defense mechanism is the need of the hour. Our Immune power has to be made stronger to such an extent that it can fight very effectively and efficiently those germs and microbes, pernicious to our body. The Immune system has become a subject of great interest in the Medical science. Immunity, also known as Defence Mechanism, is a widely researched and discussed topic in the field of medicine. When the Defence Mechanism gets aborted, all kinds of diseases especially due to various microbes occur and concomitantly they destroy the host also. The protection and timely boosting of the Immune system is therefore inevitable for disease free life. Though Modern Medical Science is working hard to develop a harmless solution to boost Human Immunity, a lot of work remaining tobe done. From out of Research and Development done on managing immune system using traditional formulation is the development of S.I.V.A Herbal Drops from Dr. JRK's Siddha Research and Pharmaceuticals Pvt Ltd. S.I.V.A Herbal Drops is a Breakthrough formulation in the treatment of immune compromising diseases like Psoriasis, Vitiligo ect.. Siddha System of medicine prevalent and practiced mostly in South India is a system of medicine with 3000 years of heritage. Many of the formulations are rarely found in Ayurveda and other Indian System of medicine. One such formulation is SIVANAR VEMBU KUZHI THAILAM (S.I.V.A), bitter tasting oil extracted by novel research process of Dr. JRK's Siddha Research and Pharmaceuticals Pvt Ltd. This is a new and most needed drug for Immuno compromising diseases .

S.I.V.A Herbal Tonic

S.I.V.A Herbal Tonic

Indications For Children of 1 yr – 12yr age group: Upper respiratory tract infections Digestive problems. Food refusal due to lack of appetite Inadequate assimilation of nutrients   Composition Each 5 ml contains extracts of: Indigofera aspalathoides : 10mg Celastrus paniculatus : 10mg Corallocarpus epigaeus : 10mg Solanum trilobatum : 50mg Ocimum sanctum : 50mg Wrightia tinctoria : 10mg Bacopa monnnieri : 10mg Piper longum : 10mg Piper nigrum : 10mg Zingiber officinale : 10mg Tinospora cordifolia : 10mg Leucas aspera : 50mg Piper betle : 10mg Syrup base : QS   Mechanism of action Boosts immune defence against pathogens Improves digestive function Stimulates appetite Improves assimilation of nutrients   Dosage / Administration 1 to 3 yrs : 10 ml once daily before food. 4 yrs and above: 10 ml Twice daily before food   Benefits of product A unique formulation for immune boosting and immune protection in children Addresses the common Health problems of the pediatric age group from 1 yr to 12 yrs Continuous use prevents recurrence of upper respiratory tract infections Improves appetite and digestion and thus helps to gain weight in children No known side effect in prescribed dosage Presentation : 200 ml pack Contraindication There are no known contraindication.

TOLENORM - Products for Vitiligo

TOLENORM Oil and TOLENORM Ointment Tolenorm Oil and Ointment is a proven solution to the problem of Vitiligo and hypopigmentary problems. Tolenorm Oil & Ointment comes to you after successful clinical research and trials on over 100 patients suffering from vitiligo and hypopigmentary problems in the OPD of Dr.JRK's Research wing. TOLENORM OIL Indications Vitiligo Hypo-pigmentary problems Composition Each 5 ml contains Extracts of: Wrightia tinctoria : 50mg Psoralea corylifolia : 50mg Indigofera tinctoria : 50mg Piper longum : 50mg Oleum Cocos nucifera : QS Mechanism of action Augments tyrosinase activity at pre and post transcription levels Augments alpha MSH activity. (Melanocyte stimulating Hormone) Increases dendrite effect of melanocytes Enhances melanocyte migration Usage Instruction Apply tolenorm oil on affected areas. After absorption of the oil on skin, the patient may opt to expose the sunlight for about 3-5 minutes. Thereafter, apply tolenorm ointment over depigmented areas. Benefits of product Restores skin pigmentation in vitiligo patients Fast onset of re-pigmentation, usually within 6-8 weeks Effective way to get natural skin color for vitiligo patients Safe for prolonged use in long term usage High success rate TOLENORM OINTMENT Indications Vitiligo Hypo-pigmentary problems Composition Each 5 gm contains Extracts of: Wrightia tinctoria : 25mg Psoralea corylifolia : 25mg Indigofera tinctoria : 100mg Oitmentbase base with Oleum cocos nucifera : QS Mechanism of action Augments tyrosinase activity at pre and post transcription levels Augments alpha MSH activity. (Melanocyte stimulating Hormone) Increases dendrite effect of melanocytes Enhances melanocyte migration Usage Instruction Apply tolenorm oil on affected areas. After absorption of the oil on skin, the patient may opt to expose the sunlight for about 3-5 minutes. Thereafter, apply tolenorm ointment over depigmented areas. Benefits of product Fast onset of re-pigmentation, usually within 6-8 weeks Effectively restores natural skin colour Safe for prolonged use in long term usage High success rate Tolenorm oil and Tolenorm Ointment are 100 % safe, non-toxic, herbal preparations with no side effects Tolenorm Oil is available as 50ml and 100ml PET Containers. Tolenorm Ointment is available as 35gm and 75gm tubes. Contraindication There are no known contraindication.                       For more details, please visit us,               http://www.jrksiddha.com

Burns and Scalds

Superficial Thickness Burn Problem Solution Usage instruction Burns and Scalds Thee Gel Apply gently over affected areas immediately after cleansing and continue application twice a day until remission. While application do not rub or massage. Thee Gel is specially formulated with the triple benefits of instant cooling, wound healing and antiseptic property. Thee Gel instantly cools the damaged surface and the key actives enhances cell migration process to facilitate the healing. The antiseptic property offers aseptic benefit. For more details, please visit us, http://www.jrksiddha.com

Research findings of - CARATOL - E CAPSULES

Studies and evaluation done on Caratol - E Capsules

Treatment of Vitiligo is a major problem as its genesis is multifaceted. Recovery of pigments (melanocytes proliferation and melanin induction) and ultimately immunomodulation are essential for the complete cure of Vitiligo.

Topical application of TOLENORM (Extracts of Psoralia corylifolia, Wrightia tinctoria and indigofera tinctoria) has been found to be an effective preparation in the treatment of Vitiligo and well accepted amongst practicing Dermatologists. TOLENORM is a proprietary formulation from Dr. JRK's Siddha Research and Pharmaceuticals Pvt Ltd.Caratol - E has been recommended for concurrent therapy with Topical Tolenorm.

Now, the results of a study conducted and published has conclusively proved that the combination therapy of Tolenorm and Caratol- E improves melanocytes proliferation and has an immunomodulatory performance both being essential factors for repigmentation amongst Vitiligo patients.

Extract of study done are presented below:

The study revealed that nearly 90% of the patients commenced re-pigmentation within 12 weeks in treatment with Tolenorm alone. In combination with Caratol - E, the commencement of re-pigmentation process was faster (10 weeks) and with a higher % of re-pigmentation (25% compared to 15%). Overall, at the end of 50 weeks, the % regimentations in combination treatment were 82.5% as against 55% with Tolenorm alone.

The results of treatment with Tolenorm alone are by themselves very good. It only gets better and faster in combination with Caratol - E.

Ref: Dr. J.R. Krishnamoorthy, Dr. S. Ranganathan, "Clinical and experimental study on certain herbal, mineral and metal compounds used in Siddha Medicine for management of Vitiligo" Journal of Research in Ayurveda and Siddha, PP 1-11, Vol. XXII No 1-2 Jan-June 2001, Published by Central Council for Research in Ayurveda and Siddha, Ministry of Health and Family Welfare, Govt. of In

For more details, please visit us,

http://www.jrksiddha.com

Pesin Capsules

Effective for auto-immune disorders and immune deficient conditions

In the treatment of

Psoriasis Auto immune disorders

Composition Each 500mg capsule contains Extract of: Smilax chinensis : 100 mg Embelia ribes : 100 mg Withania somnifera : 125 mg Elettaria cardamomum : 100 mg Conch turbinella - rapa parpam : 50 mg Linga chenduram : 1 mg Excipients : QS

Dosage / Administration ·         Adults: One capsule in morning and two capsules at night after food ·         Children: Above 10 years: One capsule a day after food

Lumina Herbal Shampoo

Lumina Herbal Shampoo For 100% Healthy Hair

For Lustrous and dandruff free hair

Composition:

Each 5mg contains Extract of Acacia Sinuate :10 mg Aloe vera :  2 mg Trigonella Foenum :  2 mg Hibiscus Rosa-sinensis :  5 mg Indigofera tinctoria :  5 mg Psoralea corylifolia :  2 mg

 Apply Lumina Herbal Shampoo on wet scalp and generate lather, using soft water clean the scalp there after. Dry hair with soft cloth before combing. Use Lumina shampoo for a dandruff free lustrous hair. Its natural and refreshing smell would make your day a pleasant one.

For more details, please visit us,

http://www.jrksiddha.com

Solution for Immune Related Problems

Problem Solution Usage instruction Immune Boosting S.I.V.A Herbal Drops Adult: 10 drops preferably honey in empty stomach twice a day. S.I.V.A Herbal Tonic for Pediatric use 1 to 3 years- 10ml once daily before food.4 years and above: 10ml twice daily before food.

In today's jet-set life style, due to change of food habits from natural to junk , shift of work hour drastically and hence change of biological clock of our body , home and work related stress etc coupled with continuous exposure to different types of pollution, there is obvious onslaught of whole host of germs and microbes round the clock on our body . Hence you will agree that developing a strong, robust body- defense mechanism is the need of the hour. Our Immune power has to be made stronger to such an extent that it can fight very effectively and efficiently those germs and microbes, pernicious to our body. The Immune system has become a subject of great interest in the Medical science. Immunity, also known as Defence Mechanism, is a widely researched and discussed topic in the field of medicine. When the Defence Mechanism gets aborted, all kinds of diseases especially due to various microbes occur and concomitantly they destroy the host also. The protection and timely boosting of the Immune system is therefore inevitable for disease free life. Though Modern Medical Science is working hard to develop a harmless solution to boost Human Immunity, a lot of work remaining tobe done. From out of Research and Development done on managing immune system using traditional formulation is the development of S.I.V.A Herbal Drops from Dr. JRK's Siddha Research and Pharmaceuticals Pvt Ltd. S.I.V.A Herbal Drops is a Breakthrough formulation in the treatment of immune compromising diseases like Psoriasis, Vitiligo ect.. Siddha System of medicine prevalent and practiced mostly in South India is a system of medicine with 3000 years of heritage. Many of the formulations are rarely found in Ayurveda and other Indian System of medicine. One such formulation is SIVANAR VEMBU KUZHI THAILAM (S.I.V.A), bitter tasting oil extracted by novel research process of Dr. JRK's Siddha Research and Pharmaceuticals Pvt Ltd. This is a new and most needed drug for Immuno compromising diseases.

Research findings of - G - 7 CAPSULES

Studies and evaluation done on G - 7 Capsule presented here are proprietary formulation of Dr. JRK's Siddha Research and Pharmaceuticals Pvt Ltd

Anti allergenic study of G - 7 Capsule

G-7 capsule, the proprietary formulation of Dr.JRK's Siddha Research and Pharmaceuticals Pvt.Ltd., Kuntrathur, Chennai was studied. Both In vitro and In vivo study was carried out for confirmation. The peritoneal mast cells were used for the in vitro study. The isolated mast cells were maintained in RPMI 1640 tissue culture medium in a flat bottom multi welled micro titre plate. The cells were treated with different concentrations of G-7 extract prepared in Hans buffer with the aid of Myosol as solvent. The concentrations of the G-7 tested were 2,10,20,40 and 50 µg / ml of medium. The treatment time was kept constant for 20 minutes. Later, the cells were challenged with sensitized IgE and the opsonized allergen. The amount of histamines and neutral proteases released by the G-7 treated and untreated mast cells were quantified. Histamine quantification was done by radio immune assay using radio tagged antihistamines using Scintillation counter. Similarly, attempts were made to check the histamine release by using specific immune staining.

Treatment Quantity of Histamine released Protease activity Treated Group 40µg / ml 60 IU / 100 cells 18.3 mg / ml / minute Untreated Group 123 IU / 100 cells 28 mg / ml / minute

Proteolytic activity was determined by substrate-enzyme reaction assay. The end product the tyrosine released as a result of proteolyses of collagen is determined. Determination of mechanism of action The IgE – FC receptor site in the mast cells were blocked with a dummy protein prior to G-7 treatment. The dummy protein is later removed and was challenged with sensitized IgE. The findings revealed that the degranulation inhibition is mediated through IgE receptor binding by the G-7 moiety. In vivo study Dust inhalation study For in vivo confirmation of the effect of G-7 in mast cell degranulation inhibition, dust inhalation study was conducted using Rabbit model. Rabbits were pre-treated with G-7 for 15 days. Later the treated and untreated animals were challenged with house dust through a nebulizer in a dust inhalation chamber. The histamine released in the system is assayed as mentioned above. The findings of the study reveal that G-7 offers greater protective effect to the mast cells from degranulation during the allergen exposure Inhibition of broncho spasm during allergen exposure and anaphylactic shock in the case of - G -7 treated animals also observed in a separate study. Mechanism of action of G - 7 on mast cells